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JRA 競走馬総合研究所

トップページ > 研究室紹介 > 臨床医学研究室 Clinical Veterinary Medicine Division

研究室紹介

臨床医学研究室 Clinical Veterinary Medicine Division

すべての競走馬に最高水準の医療技術を!

臨床医学研究室イメージ

臨床医学研究室では、競走中あるいは調教中に発症する競走馬の様々な疾病の診断法、予防法、治療法の開発に関する研究を行っています。これらの研究活動を通じ、疾病を発症したすべての馬を競走復帰させることを最終目標としています。そのため、当研究室に所属するメンバーの専門分野は、外科、内科、スポーツ医学、リハビリテーション医学、麻酔学、臨床薬理学、臨床疫学、臨床統計学など多岐に渡ります。これまでも、JRA栗東/美浦トレーニング・センターや競走馬リハビリテーションセンターに所属する臨床獣医師と連携し、多くの研究課題に取り組んできました。また、当研究室は若手獣医師や学生の教育機関としての役割も果たしています。

The Clinical Veterinary Medicine Division focuses on developing new methods of diagnosis, prevention and treatment for various diseases occurring during racing or training. The final goal of our research is to return all injured horses to the racecourse. The members of our laboratory have a wide range of specialties, including surgery, internal medicine, sports medicine, rehabilitation medicine, anesthesiology, clinical pharmacology, clinical epidemiology, clinical statistics. We have worked on many research projects in collaboration with clinical veterinarians of the JRA Ritto and Miho Training Centers and the Rehabilitation Research Center. Our laboratory also serves as an educational institution for young veterinarians and students.

パンフレットPamphlet(PDF)

研究スタッフ Members

  • 室長Manager太田  稔Minoru OHTA, DVM, PhD
  • 主任研究役Chief researcher黒田 泰輔Taisuke KURODA, DVM, PhD
  • 主査Researcher野村 基惟Motoi NOMURA, DVM, PhD
  • 主査Researcher三田 宇宙Hiroshi MITA, DVM

研究課題 Research Project

一般研究(2023-2027)
競走馬の各種疾病に対する臨床技術の向上に資するための基礎研究
一般研究(2024-2025)
術部感染症に対する生体分解性抗菌薬徐放製剤の応用に関する研究
一般研究(2024-2026)
多剤耐性菌感染症に対する抗菌薬投与法の検討
委託研究(2022-2024)
バイオ3Dプリンタ技術を用いたウマ軟骨組織の再建技術の開発

原著論文 Publications

2024

Kuroda T, Minamijima Y, Niwa H, Mita H, Tamura N, Fukuda K, Toutain PL, Ohta M
Pharmacokinetics/pharmacodynamics cut-off determination for fosfomycin using Monte Carlo simulation in healthy horses
J Vet Med Sci 86, 413-420, 2024 [PubMed]

Minamijima Y, Kuroda T, Kamiya T, Sone Y, Wakuno A, Ito H, Nomura M, Leung GN, Kinoshita K, Yamada M
Evaluation of plasma and urine pharmacokinetics of tranexamic acid for equine medication control
J Vet Pharmacol Ther 47, 21-27, 2024 [PubMed]

2023

Kuroda T, Minamijima Y, Niwa H, Mita H, Tamura N, Fukuda K, Ohta M
Pharmacokinetic/pharmacodynamic analysis of cephalothin after intramuscular administration in Thoroughbred horses
J Equine Sci 34, 111-114, 2023 [PubMed]

Tsubata T, Suzuyama H, Chiba K, Mita H, Tamura N, Matsukawa M
Axial transmission technique for screening bucked shin in a horse leg
Jpn J Appl Phys 62, SJ1026, 2023

Tamura N, Heidari N, Faragher RGA, Smith RKW, Dudhia J
Effects of resveratrol and its analogues on the cell cycle of equine mesenchymal stem/stromal cells
J Equine Sci 34, 67-72, 2023 [PubMed]

Mita H, Kuroda T, Niwa H, Tamura N, Fukuda K, Ohta M
Incidence of surgical site infection after internal fixation of the first phalangeal bone and the third metacarpal/metatarsal bone fractures in Thoroughbred racehorses
J Equine Sci 34, 61-66, 2023 [PubMed]

Lallemand EA, Bousquet-Mélou A, Chapuis L, Davis J, Ferran AA, Kukanich B, Kuroda T, Lacroix MZ, Minamijima Y, Olsén L, Pelligand L, Portugal FR, Roques BB, Santschi EM, Wilson KE, Toutain PL
Pharmacokinetic-pharmacodynamic cutoff values for benzylpenicillin in horses to support the establishment of clinical breakpoints for benzylpenicillin antimicrobial susceptibility testing in horses
Front Microbiol 14, 1282949, 2023 [PubMed]

Seki N, Tochinai R, Sekizawa SI, Márquez MA, Fukuda K, Ohmura H, Kuwahara M
Preliminary study of heart rate variability in Criollo horses for the elucidation of their neurophysiological characteristics of autonomic nerve function
J Equine Sci 34, 55-59, 2023 [PubMed]

Fukuda K, Mita H, Tamura N, Kuroda T, Kuwano A, Takahashi T, Sato F
Characteristic inflammatory biomarkers in an equine model of persistent synovitis induced by the intra-articular administration of monoiodoacetic acid
J Equine Vet Sci 127, 104564, 2023 [PubMed]

Urayama S, Tanaka A, Kusano K, Sato H, Muranaka M, Mita H, Nagashima T, Matsuda H
Oral administration of meloxicam and flunixin meglumine have similar analgesic effects after lipopolysaccharide-induced inflammatory response in Thoroughbred horses
J Equine Vet Sci 121, 104205, 2023 [PubMed]

Kuroda T, Minamijima Y, Mita H, Tamura N, Fukuda K, Kuwano A, Toutain PL, Sato F
Rational determination of cefazolin dosage regimen in horses based on PK/PD principles and Monte Carlo simulations
J Vet Pharmacol Ther 46, 62-67, 2023 [PubMed]

2022

Kondo T, Sato F, Tsuzuki N, Watanabe K, Horiuchi N, Kobayashi Y, Yamada K
Characteristic computed tomographic myelography findings in 23 Thoroughbred horses
J Vet Med Sci 84, 525-532, 2023 [PubMed]

Miyashita K, Suzuyama S, Chiba K, Osaki M, Mita H, Tamura N, Matsukawa M
Study on ultrasonic wave propagation in equine leg bone for screening bucked shin
J Acoust Soc Am 152, 890-898, 2022 [PubMed]

Ishii H, Shibuya M, Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Sato F, Kuroda T, Yamada M, Leung GN
Pharmacokinetic study of vadadustat and high-resolution mass spectrometric characterization of its novel metabolites in equines for the purpose of doping control
Curr Drug Metab 23, 850-865, 2022 [PubMed]

Ishii H, Shibuya M, Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Sato F, Kuroda T, Yamada M, Leung GN
Generic approach for the discovery of drug metabolites in horses based on data‑dependent acquisition by liquid chromatography high‑resolution mass spectrometry and its applications to pharmacokinetic study of daprodustat
Anal Bioanal Chem 414, 8125-8142, 2022 [PubMed]

Minamijima Y, Tozaki T, Kuroda T, Urayama S, Nomura M, Yamamoto K
A comprehensive and comparative proteomic analysis of horse serum proteins in colitis
Equine Vet J 54, 1039-1046, 2022 [PubMed]

Kuroda T, Minamijima Y, Niwa H, Mita H, Tamura N, Fukuda K, Kuwano A, Sato F
Concentration of cephalothin in body fluids and tissue samples in Thoroughbred horses
J Equine Sci 33, 51-54, 2022 [PubMed]

Kuroda T, Minamijima Y, Nomura M, Yamashita S, Yamada M, Nagata S, Mita H, Tamura N, Fukuda K, Kuwano A, Kusano K, Toutain PL, Sato F
Medication control of flunixin in racing horses: Possible detection times using Monte Carlo simulations
Equine Vet J 54, 979-988, 2022 [PubMed]

Mita H, Tamura N, Fukuda K, Kuroda T, Kuwano A, Sato F
Incidence of carpal fractures and risk factors for recurrent fractures after arthroscopic removal of carpal chip fracture fragments in Thoroughbred racehorses
Vet Rec 190, e1482, 2022 [PubMed]

Fukuda K, Kuroda T, Tamura N, Mita H, Miyata H, Kasashima Y
Platelet lysate enhances equine skeletal muscle regeneration in a bupivacaine-induced muscle injury model
J Equine Vet Sci 112, 103892, 2022 [PubMed]

Kondo T, Sato F, Tsuzuki N, Watanabe K, Horiuchi N, Kobayashi Y, Yamada K
Characteristic computed tomographic myelography findings in 23 Thoroughbred horses
J Vet Med Sci 84, 525-532, 2022 [PubMed]

Iimori M, Tamura N, Seki K, Kasashima Y
Relationship between the ultrasonographic findings of suspected superficial digital flexor tendon injury and the prevalence of subsequent severe superficial digital flexor tendon injuries in Thoroughbred horses: a retrospective study
J Vet Med Sci 84, 261-264, 2022 [PubMed]

2021

Sato F, Otsuka N, Kuwano A
Toe white line separation associated with the notch (crena marginalis) on the distal phalanges in Thoroughbred yearling horses
J Vet Med Sci 83, 1745–1749, 2021 [PubMed]

Kuroda T, Minamijima Y, Niwa H, Tamura N, Mita H, Fukuda K, Kaimachi M, Suzuki Y, Enoki Y, Taguchi K, Matsumoto K, Toutain PL, Bousquet-Melou A, Kasashima Y
Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses
Equine Vet J 53, 1239-1249, 2021 [PubMed]

Ninomiya S, Mita T, Nagamune S, Shimizu C, Fukano Y, Sato F
Negative correlation of suckling behaviour and foal weight gain during the first week after birth
Appl Anim Behav Sci 234,105200, 2021

Kitaura T, Sato F, Hada T, Ishimaru M, Kodama R, Nambo Y, Watanabe G, Taya K
Influence of exercise and emotional stresses on secretion of prolactin and growth hormone in Thoroughbred horses
J Equine Sci 32, 49-53, 2021 [PubMed]

Fawcett JA, Innan H, Tsuchiya T, Sato F
Effect of advancing age on the reproductive performance of Japanese Thoroughbred broodmares
J Equine Sci 32, 31-37, 2021 [PubMed]

Tsuchiya T, Noda R, Ikeda H, Maeda M, Sato F
Relationship between endogenous plasma adrenocorticotropic hormone concentration and reproductive performance in Thoroughbred broodmares
J Vet Int Med 35, 2002-2008, 2021 [PubMed]

Tozaki T, Ohnuma A, Takasu M, Nakamura K, Kikuchi M, Ishige T, Kakoi H, Hirora K, Tamura N, Kusano K, Nagata S
Detection of non-targeted transgenes by whole-genome resequencing for gene-doping control
Gene Therapy 28, 199-205, 2021 [PubMed]

2020

Fukuda K, Kuwano A, Kuroda T, Tamura N, Mita H, Okada Y, Kasashima Y
Optimal double-spin method for maximizing the concentration of platelets in equine platelet-rich plasma
J Equine Sci 31, 105-111, 2020 [PubMed]

Kuroda T, Nagata S, Tamura N, Kinoshita Y, Niwa H, Mita H, Minami T, Fukuda K, Hobo S, Kuwano A
Single-dose pharmacokinetics of orally administered metronidazole and intravenously administered imipenem in healthy horses and computer-based simulation of pleural fluid concentrations with multiple dosing
Am J Vet Res 81, 783-789, 2020 [PubMed]

Fukuda K, Kuroda T, Tamura N, Mita H, Kasashima Y
Optimal activation methods for maximizing the concentrations of platelet-derived growth factor-BB and transforming growth factor-β1 in equine platelet-rich plasma
J Vet Med Sci 82, 1472-1479, 2020 [PubMed]

Nomura M, Kuroda T, Tamura N, Muranaka M, Niwa H
Mortality, clinical findings, predisposing factors and treatment of Clostridioides difficile colitis in Japanese Thoroughbred racehorses
Vet Rec 187, e14, 2020 [PubMed]

Tamura N, Okano A, Kuroda T, Niwa H, Kusano K, Matsuda Y, Fukuda K, Mita H, Nagata S
Utility of systemic voriconazole in equine keratomycosis based on pharmacokinetic-pharmacodynamic analysis of tear fluid following oral administration
Vet Ophthalmol 23, 640-647, 2020 [PubMed]

2019

Ninomiya H, Kuwano A
Microvasculature of the guttural pouch mucosa and relationship with the internal carotid artery in horses
J Equine Vet Sci 74, 84-89, 2019

Kuroda T, Nagata S, Tamura N, Mita H, Kusano K, Mizobe F, Takizawa Y, Fukuda K, Kasashima Y
Pharmacokinetics and pharmacodynamics of olopatadine following administration via nasogastric tube to healthy horses
Am J Vet Res 80, 689-695, 2019 [PubMed]

Yokomori T, Tozaki T, Mita H, Miyake T, Kakoi H, Kobayashi Y, Kusano K, Itou T
Heritability estimates of the position and number of facial hair whorls in Thoroughbred horses
BMC Res Notes 12, 346, 2019 [PubMed]

2018

Tamura N, Kodaira K, Yoshihara E, Mae N, Yamazaki Y, Mita H, Kuroda T, Fukuda K, Tomita A, Kasashima Y
A retrospective cohort study investigating risk factors for the failure of Thoroughbred racehorses to return to racing after superficial digital flexor tendon injury
Vet J 235, 42-46, 2018 [PubMed]

Nomura M, Mizobe F, Kato T, Kuroda T, Urayama S, Muranaka M
Evaluating continuous blood coagulopathy in assessing the severity of acute colitis in Thoroughbred racehorses
J Equine Sci 29, 79-85, 2018 [PubMed]

2017

Tamura N, Kuroda T, Kotoyori Y, Fukuda K, Nukada T, Kato T, Kuwano A, Kasashima Y
Application of sonoelastography for evaluating the stiffness of equine superficial digital flexor tendon during healing
Vet Rec 180, 120, 2017 [PubMed]
 
Tamura N, Nukada T, Kato T, Kuroda T, Kotoyori Y, Fukuda K, Kasashima Y
The use of sonoelastography to assess the recovery of stiffness after equine superficial digital flexor tendon injuries: A preliminary prospective longitudinal study of the healing process
Equine Vet J 49, 590-595, 2017 [PubMed]

Fukuda K, Miyata H, Kuwano A, Kuroda T, Tamura N, Kotoyori Y, Kasashima Y
Does the injection of platelet-rich plasma induce changes in the gene expression and morphology of intact Thoroughbred skeletal muscle?
J Equine Sci 28, 31-39, 2017 [PubMed]

2016

Kuroda T, Kinoshita Y, Niwa H, Shinzaki Y, Tamura N, Hobo S, Kuwano A
Meticillin-resistant Staphylococcus aureus colonisation and infection in Thoroughbred racehorses and veterinarians in Japan
Vet Rec 178, 473, 2016 [PubMed]

2015

Tanaka K, Hiraga A, Takahashi T, Kuwano A, Morrison SE
Effects of aluminum hinged shoes on the structure of contracted feet in Thoroughbred yearlings
J Equine Sci 26, 67-71, 2015 [PubMed]
 
Sasao T, Fukuda Y, Yoshida S, Miyabara S, Kasashima Y, Kuwano A, Arai K
Population doubling level-dependent change of secreted glycosaminoglycan in equine bone marrow-derived mesenchymal stem cells
J Equine Sci 26, 73-80, 2015 [PubMed]
 
Kuroda T, Kinoshita Y, Niwa H, Mizobe F, Ueno T, Kuwano A, Hatazoe T, Hobo S
Methicillin-resistant Staphylococcus aureus ulcerative keratitis in a Thoroughbred racehorse
J Equine Sci 26, 95-98, 2015 [PubMed]
 
Hatazoe T, Endo Y, Iwamoto Y, Korosue K, Kuroda T, Inoue S, Murata D, Hobo S, Misumi K
A study on the distribution of color Doppler flows in superficial digital flexor tendon of young Thoroughbreds during training periods
J Equine Sci 26, 99-104, 2015 [PubMed]

学会発表 Conference presentation

2023

田村周久
ウマ間葉系幹細胞の凝集体を用いたウマ浅屈腱炎の治療
第9回細胞凝集研究会 2023.12

Mita H, Kuroda T, Minamijima Y, Tamura N, Ohta M
Concentration of marbofloxacin insubcutaneous tissue fluid aftersubcutaneous administration ofmarbofloxacin encapsulated microparticles
2023 American College of Veterinary Surgeons(ACVS) Surgery Summit 2023.10

Kuroda T, Minamijima Y, Niwa H, Mita H, Tamura N, Fukuda K, Toutain PL, Ohta M
A rational determination of cefazolindosage regimen in horses based on PK/PDprinciples and Monte Carlo simulations
15th International Congress of the European Association of Veterinary Pharmacology and Toxicology (EAVPT 2023) 2023.7

Tamura N, Dudhia J, Heidari N, Smith RKW, Faragher RGA
Effects of resveratrol and its analogues onthe cell cycle of equine mesenchymal stemcells
Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU 2023) 2023.3

Fukuda K, Mita H, Tamura N, Kuroda T, Sato F
Platelet lysates does not exert anti-inflammatory effect on monoiodoaceticacid-induced equine persistent synovitis
Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU 2023) 2023.3

2022

Kuroda T, Minamijima Y, Niwa H, Mita H, Tamura N, Fukuda K, Toutain PL, Ohta M Pharmacokinetics/pharmacodynamics cutoff for fosfomycin using Monte Carlo simulation in healthy horses 11th International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM) 2022.9

2021

桑野睦敏
ウマの蹄
第8回日本獣医病理学専門家協会学術集会 2021.3


黒田泰輔・南島陽平・丹羽秀和・三田宇宙・田村周久・福田健太郎・桑野睦敏・Toutain PL・佐藤文夫
ウマにおける第1世代セファロスポリンのVetCAST approachに基づくPK/PDブレイクポイントの解析
第164回日本獣医学会学術集会 2021.9

福田健太郎・黒田泰輔・田村周久・三田宇宙・桑野睦敏・佐藤文夫
モノヨード酢酸(MIA)関節内投与法によるウマ持続的滑膜炎モデルの確立と滑膜炎症マーカー発現の変化
第36回日本整形外科学会基礎学術集会 2021.10

Tamura N, Mita H, Fukuda K, Kuroda T, Sato F, Kuwano A, Tabata Y, Kasashima Y
Aggregates of equine mesenchymal stem cells with gelatin hydrogel for regenerative therapy of tendon injury
6th World Congress of the Tissue Engineering and Regenerative Medical International Society 2021. 11

桑野睦敏・三田宇宙・草野寛一・栗東TC蟻洞調査チーム・美浦TC蟻洞調査チーム
競走馬の蟻洞の発生状況および発生要因の解明
日本ウマ科学会第34回学術集会 2021.12

福田健太郎・田村周久・黒田泰輔・三田宇宙・桑野睦敏・佐藤文夫
ウマ自己調整血清(ACS)と多血小板血漿(PRP)のサイトカイン特性比較
日本ウマ科学会第34回学術集会 2021.12

黒田泰輔
競走馬のアレルギー疾患および感染症に対する治療法の研究(奨励賞受賞講演)
日本ウマ科学会第34回学術集会 2021.12

2020

福田健太郎・黒田泰輔・田村周久・笠嶋快周
ウマ多血小板血漿(PRP)の最適な活性化条件についての検討
日本獣医再生医療学会第15回年次大会 2020.1

田村周久・福田健太郎・黒田泰輔・三田宇宙・桑野睦敏・田畑泰彦・高橋敏之・笠嶋快周
自己骨髄由来間葉系幹細胞の凝集体を用いたウマ浅屈腱炎に対する再生医療
日本獣医再生医療学会第15回年次大会 2020.1

三田宇宙・福田健太郎・黒田泰輔・田村周久・桑野睦敏・高橋敏之
日本のサラブレッド種競走馬における腕節構成骨剥離骨折の発症状況および関節鏡下骨片摘出術後の予後に骨折部位が与える影響
第99回日本獣医麻酔外科学会 2020.1

桑野睦敏・上野孝範・桂嶋勇輔・村中雅則・立野大樹・斎藤重彰
四肢蹄に同時に発生した蹄全周性脆弱蹄壁におけるセレニウム沈着の証明
令和元年度日本獣医師会獣医学術学会年次大会 2020.2

福田健太郎・黒田泰輔・田村周久・三田宇宙・佐藤文夫・宮田浩文・笠嶋快周
ウマ多血小板血漿(PRP)療法は筋修復を促進させるか
第163回日本獣医学会学術集会 2020.9

桑野睦敏・上野孝範・桂嶋勇輔・村中雅則・立野大樹・斎藤重彰
アルカリ病を発症した競走馬の蹄病変におけるセレニウム沈着の証明
日本ウマ科学会第33回学術集会 2020.11

Kuroda T, Minamijima Y, Tamura N, Mita H, Fukuda K, Toutain PL, Bousque-Melou A
Rational dosage regimen for cephalothin and cepfazolin using pharmacokinetic and pharmacodynamic analysis in healthy thoroughbred horses
10th International Conference on Antimicrobial Agents in Veterinary Medicine 2020. 11

2019

Kasashima Y, Tamura N, Fukuda K, Kuroda T, Mita H
How long do implanted mesenchymal stem cell exist at injury site in tendon with acute and chronic inflammation phase?
2019 North American Veterinary Regenerative Medicine Association Conference 2019.9

Tamura N, uroda T, Fukuda K, Mita H, Tabata Y, Kasashima Y
Use of mesenchymal stem cell aggregates with gelatin hydrogel microspheres for regenerative therapy of tendon injury in equine practice
2019 North American Veterinary Regenerative Medicine Association Conference 2019.9

福田健太郎・黒田泰輔・田村周久・三田宇宙・高橋敏之・笠嶋快周
筋損傷部位に投与されたウマ多血小板血漿(PRP)の残存性と組織に及ぼす影響について
第162回日本獣医学会学術集会 2019.9

高橋敏之・平賀 敦
最近30年間のサラブレッド競走馬の走速度変化
日本ウマ科学会第32回学術集会 2019.11

高橋敏之
シンポジウム「動物の運動における代謝 - 遺伝」
競走馬のバイオメカニクス
日本動物遺伝育種学会第20回大会 2019.12

2018

笠嶋快周
「獣医師が行う再生医療研究~小・大動物臨床への応用から畜産・動物保護~」
ウマの浅指屈筋健損傷に対する幹細胞移植治療の基礎研究と臨床応用
第17回日本再生医療学会総会 2018.3

黒田泰輔
競走馬におけるセファロスポリンのPK/PDに基づいた最適投与法の検討
第66回日本化学療法学会 2018.6

Kasashima Y, Tamura N, Fukuda K, Kuroda T, Mita H, Tabata T, Arai K
Stem cell therapy for tendon injury of racehorses in Japan: Present conditions and future prospects
18th Congress of International Society for Animal Clinical Pathology, ISACP 2018 Tokyo 2018.8

Kasashima Y, Tamura N, Fukuda K, Kuroda T, Tomita A
How long do implanted mesenchymal stem cell exist at injury site in tendon tissue?: a cell tracking study
5th World Congress of Tissue Engineering and Regenerative Medicine International Society 2018.9

Fukuda K, Tamura N, Kuroda T, Tomita A, Kasashima Y
Effect of different activation methods on release of transforming growth factor-1 and platelet-derived growth factor-BB from equine platelet-rich plasma
5th World Congress of Tissue Engineering and Regenerative Medicine International Society 2018.9

Tamura N, Kuroda T, Fukuda K, Tomita A, Tabata Y, Kasashima Y
Mesenchymal stem cells aggregates with gelatin hydrogel microspheres for regenerative therapy of tendon injury in equine practice
5th World Congress of Tissue Engineering and Regenerative Medicine International Society 2018.9

黒田泰輔・南島陽平・榎木裕紀・松元一明・丹羽秀和・田村周久・三田宇宙・福田健太郎・笠嶋快周
ウマにおけるβラクタム系抗菌薬のPK/PDに基づいた投与法の検討
第161回日本獣医学会学術集会 2018.9

Kasashima Y, Tamura N, Kuroda T, Fukuda K, Mita H, Tomita A
Injection of stem cells into injured tendon results in limited retention and distribution of cells
5th International Scientific Tendinopathy Symposium 2018.9

Tamura N, Kuroda T, Fukuda K, Mita H, Tabata Y, Kasashima Y
Use of mesenchymal stem cells aggregates with gelatin hydrogel microspheres for regenerative therapy of tendon
5th International Scientific Tendinopathy Symposium 2018.9

Kuroda T, Nagata S, Kinoshita Y, Niwa H, Tamura N, Fukuda K, Kasashima Y
Pharmacokinetic/pharmacodynamic analysis of metronidazole and imipenem for Bacteroides spp infection of pleural cavity in horses
9th International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM) 2018.10

2017

田村周久・黒田泰輔・福田健太郎・冨田篤志・田畑泰彦・笠嶋快周
ゼラチンマイクロスフィアとウマ間葉系幹細胞を用いて作製した細胞凝集体に関する検討
第16回日本再生医療学会総会 2017.3

Kuroda T, Nagata S, Tamura N, Fukuda K, Tomita A, Kasashima Y
Olopatadine, a second-generation antihistamine, has high antihistaminic effect from pharmacokinetics/pharmacodynamics analysis in horses
American Veterinary Medical Association (AVMA) Convention 2017 2017.7

福田健太郎・冨田篤志・黒田泰輔・田村周久・笠嶋快周
ウマ多血小板血漿(PRP)の最適な活性化方法についての検討
第160回日本獣医学会学術集会 2017.9

田村周久・冨田篤志・福田健太郎・黒田泰輔・笠嶋快周
塩基性線維芽細胞成長因子とヘパリンがウマ幹細胞の増殖に与える影響
第160回日本獣医学会学術集会 2017.9

福田健太郎・冨田篤志・黒田泰輔・田村周久・笠嶋快周
ウマ多血小板血漿(PRP)から効率的にサイトカイン(PDGF)を得る活性化方法の検討
第9回多血小板血漿(PRP)療法研究会 2017.11

Kuroda T, Niwa H, Kinoshita Y, Tamura N, Fukuda K, Tomita A, Kasashima Y
Methicillin-resistant Staphylococcus aureus colonization and infection in Thoroughbred racehorses and equine veterinarians in Japan
American Association of Equine Practitioners (AAEP) 2017 2017.11

福田健太郎・冨田篤志・黒田泰輔・田村周久・笠嶋快周
フリーズドライ(真空凍結乾燥)で保存されたウマ多血小板血漿(PRP)中に含有されるサイトカイン濃度について -凍結保存法との比較検討-
日本ウマ科学会第30回学術集会 2017.11

2016

黒田泰輔・守山秀和・琴寄泰光・田村周久・福田健太郎・桑野睦敏・笠嶋快周
競走馬の骨折モデルに対する低出力超音波パルス療法の効果について
第159回日本獣医学会学術集会 2016.9

田村周久・吉原英留・小平和道・飯森麻衣・黒田泰輔・福田健太郎・笠嶋快周
腱内の微小血管とその後の重篤な腱損傷との関連性 -ウマを用いた検討-
第31回日本整形外科学会基礎学術集会 2016.10

Kasashima Y, Tamura N, Kotoyori Y, Fukuda K, Kuroda T, Tabata Y
Can delivery of mesenchymal stem cell aggregates enhance retention of cells at the site of injury in cell therapy of equine tendon?
International Scientific Tendinopathy Symposium 2016 2016.10

Tamura N, Yoshihara E, Kodaira K, Kuroda T, Fukuda K, Kasashima Y
Is neovascularization an indicator of subsequent tendon injury risk in the horses?
International Scientific Tendinopathy Symposium 2016 2016.10

Kasashima Y, Tamura N,Tomita A, Fukuda K, Kuroda T, Tabata Y, Arai K
Stem cell therapy for tendon injury of racehorses in Japan: Present conditions and future prospects
Havemeyer Conference on Regenerative Medicine ll 2016.11

2015

笠嶋快周・田村周久・琴寄泰光・福田健太郎・黒田泰輔・田畑泰彦・桑野睦敏
腱損傷治療を目的としたウマ間葉系幹細胞とゼラチンマイクロスフィアによる細胞凝集体の作製と移植法の検討
第14回日本再生医療学会総会 2015.3

桑野睦敏
「馬の装蹄から考えるフットケア」馬の蹄葉炎の研究的な近況
第18回護蹄研究会学術シンポジウム 2015.3

Kasashima Y, Tamura N, Kotoyori Y, Fukuda K, Kuroda T, Tabata Y, Kuwano A
Can stem cell loaded gelatin microspheres improve cell therapy for equine tendon injures?
2015 North American Veterinary Regenerative Medicine Association Conference 2015.6

笠嶋快周
「再生獣医療の進展を目指して-日本が牽引する新分野-」競走馬の腱・靭帯損傷に対する幹細胞移植治療の実際
動物用再生医療等製品の安全性試験等開発事業に係るシンポジウム 2015.9

田村周久・笠嶋快周・浅野寛文・加藤智弘・額田紀雄・石川裕博
超音波エラストグラフィを用いたウマ浅屈腱炎の修復評価
第158回日本獣医学会学術集会 2015.9

琴寄泰光・福田健太郎・桑野睦敏
デキストリン経鼻投与によるウマの食餌性蹄葉炎発症モデルの病態解析
第158回日本獣医学会学術集会 2015.9

黒田泰輔・丹羽秀和・木下優太・上野孝範・加藤智弘・桑野睦敏
競走馬におけるClostridium difficile感染症と非Clostridium difficile腸炎の特徴について
第158回日本獣医学会学術集会 2015.9

黒田泰輔
「ウマ獣医療における抗菌薬療法」JRAにおける競走馬の抗菌薬治療について
日本ウマ科学会第28回学術集会 2015.12